Drug interaction (21. combination with molecular target drugs)
نویسندگان
چکیده
منابع مشابه
Risk of drug interaction: combination of antidepressants and other drugs.
OBJECTIVE To assess the frequency of combination of antidepressants with other drugs and risk of drug interactions in the setting public hospital units in Brazil. METHODS Prescriptions of all patients admitted to a public hospital from November 1996 to February 1997 were surveyed from the hospital's data processing center in S o Paulo, Brazil. A manual search of case notes of all patients adm...
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I was preparing an extended version of our paper on Probabilistic Soft Logic (PSL) for drug-target interaction prediction [1] that was invited for submission to IEEE-TCBB journal, and it approximately coincided with the NodeXL homework. I planned to use NodeXL to find interesting observations in the dataset we used for our experimental analysis and add it to the journal submission. The followin...
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Predicting drug-target interaction using computational approaches is an important step in drug discovery and repositioning. To predict whether there will be an interaction between a drug and a target, most existing methods identify similar drugs and targets in the database. The prediction is then made based on the known interactions of these drugs and targets. This idea is promising. However, t...
متن کاملStudy of Human Albumin Protein Interaction with Fluorouracil Anticancer Drug Using Molecular Docking Method
Introduction: Drugs are mainly delivered to the target tissues by plasma proteins, such as human serum albumin, in the human body. Practical information about the thermodynamic parameters of drugs and their stability can be obtained using simulation methods, such as molecular docking. Material & Methods: This study, investigated the molecular docking of human serum albumin with fluorouracil an...
متن کاملThe Human Kinome Targeted by FDA Approved Multi-Target Drugs and Combination Products: A Comparative Study from the Drug-Target Interaction Network Perspective
The human kinome is one of the most productive classes of drug target, and there is emerging necessity for treating complex diseases by means of polypharmacology (multi-target drugs and combination products). However, the advantages of the multi-target drugs and the combination products are still under debate. A comparative analysis between FDA approved multi-target drugs and combination produc...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 2011
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma.123.147